Principal Scientist

Everlum Bio is a personalized medicine company focused on creating treatments for people with rare diseases.  We are happy to have celebrated three recent successes. We have designed and demonstrated the effectiveness of an Antisense-Oligos (ASO) to help HNRNPH2 (To Cure A Rose). We have a proof of concept gene therapy for two families with children suffering from a lysosomal storage disorder (LSD). Finally, we found a shelved drug that we are currently working to repurpose for a child with another LSD.  We are on a mission to take these successes, and so many more, to the rare community. These are exciting times at Everlum and we are hiring. 

Requirements

• Minimum of 5 years of experience in a scientific research role
• Strong background in molecular biology and genetics
• Experience with stem cell-based model systems
• Proficiency in cell culture techniques
• Expertise in assay development and optimization
• Ph.D. in a related field
• Attention to detail and strong analytical skills
• Ability to work independently and in a collaborative team environment

Full Job Description

We are seeking to bring induced pluripotent stem cell (iPSC) reprogramming and CRISPR-Cas9 mutagenesis capabilities in-house. By doing so, we aim to improve the timelines and costs associated with these critical processes. This strategic move will enable us to achieve faster turnaround times, reduce expenses and ensure higher efficiency and precision, ultimately benefiting the rare disease community we serve.  In-house CRISPR mutagenesis capabilities will allow us to perform gene editing with greater accuracy and speed, advancing our ability to develop and test new therapies.  These advancements will not only streamline our research and development processes, but also significantly lower the costs associated with these technologies. The savings and efficiencies gained will be passed on to the rare disease community, helping us deliver innovative treatments more quickly and affordably.  Our commitment to improving the quality and accessibility of preclinical research drives this initiative. By controlling these processes internally, we reaffirm our dedication to providing timely, cost-effective solutions for our rare patients.

Responsibilities

• Hands-on experience with IPSC reprogramming and CRISPR mutagenesis.
• Development of therapies to address patients’ rare diseases
• Leading scientific research projects and initiatives.
• Developing and implementing scientific strategies.
• Managing a team of scientists and researchers.
• Collaborating with other departments and external partners.
• Ensuring compliance with regulatory standards.
• Overseeing the publication of scientific papers and reports.
• Securing funding and managing budgets for scientific projects.

Why Join Us

• Innovative Environment: Be part of a cutting-edge science team dedicated to pioneering treatments for rare diseases.
• Professional Growth: Opportunities for continued education, research, and professional development.
• Impactful Work: Make a significant difference in the lives of children and their families by providing hope and improving health outcomes.
• Supportive Community: Work within a supportive and collaborative environment that values compassion, excellence, and patient-centered care.

Benefits

Paid vacation

Paid Holidays

Healthcare plan

Dental Coverage