Statistical Geneticist (Contract)

Contract  Statistical Geneticist

Serna Bio is building the world’s first map of the druggable transcriptome, systematically opening up the universe of RNA biology to small molecule drug discovery. Using our Discovery Platform, we are tackling classically intractable targets ranging from coding to non-coding RNA.

Our platform integrates human genetics data and we are looking for someone to work with our target ID team on a contract basis (with a switch to perm possible) to help accelerate our roadmap. 

Requirements

Required skills and qualifications

Here’s What You’ll Need (Minimum Qualifications)

• Ph.D. in statistical genetics with demonstrable (3+years) in genetics-databases, All of Us, UKBiobank, Gnomad etc. 
• Strong fundamentals in multivariate statistics and demonstrated track record in state-of-the-art industry methods for understanding genetic drivers of disease, and experience with databases to study genetics of diseases. 
• Demonstrated ability to develop reusable code, specifically Expertise in Bioinformatics programming and scripting languages (Python, Perl, R).
• and working with version control (e.g., git), writing tests (e.g., using pytest or testthat), and code reviews
• Experience in performing and working with results of genetically anchored studies such as GWAS, (omic)QTL, LoF, PRS, TWAS etc.
• Excellent written and oral communication skills, and previous work with clients and project-focused work

Benefits

About Us

Serna Bio is a preclinical drug discovery company developing small molecules that can modulate translation and splicing, by targeting RNA. Founded in 2021, Serna Bio leverages the convergence of synthetic biology, machine learning (ML), and massively multiplex screening to tackle the historical challenges of drugging the RNA universe.

Our core innovation lies in the Serna Discovery Platform, which systematically maps RNA structures to a vast chemical universe, generating large proprietary datasets. The platform incorporates both experimental wet lab and AI capabilities.  We use our platform to tackle undruggable targets and novel biology inaccessible by classical drug discovery. 

The Values You’ll Share 

• The Data Decides: The future of drug discovery will be computationally led. Opinions are just hypotheses. The data rules.

• Unapologetic ambition: The work we do matters. We maximise its value by striving to make the biggest impact, fastest. We don’t take the easy path, or wait for lower risk. We show up with a plan. We define what victory looks like. We make our time count.

• We don’t rely on experience, we run the experiment: We are humble in the face of work that has never been done before. We never default to experience. We use what we already know to train the machines to outperform us.

• Only the highest standards: We are inspired by challenge. We work hard. Our efforts are guided by the utility of every failed experiment and the value of new learning. Metrics matter to us. Effort, integrity, honesty, execution, and excellence are what we owe each other.

• We are one company: We operate with a ‘company first, team second’ mentality. We learn from the perspectives of others. Our is an antedisciplinary idea meritocracy. Ego is valueless. Diverse perspectives, integrity, resilience and teamwork are priceless.

• High-density, high-frequency communication: We share Work in Progress. We offer and accept critical opinions on this work so that the final versions are excellent. We communicate clearly to enable rapid decision-making, and we bring solutions, not just problems to the team.