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Senior Scientist, ADC

BioDuro-Sundia

Irvine, california


Job Details

Not Specified


Full Job Description

Job Title: Senior Scientist, ADC

Location: Shanghai, China

***Must be willing to relocate to Shanghai, China.

Salary Range: 300k-400k RMB/YR (EST. 41K-55K USD)

What We Do

BioDuro-Sundia is one of the premier Contract Research, Development and Manufacturing Organizations (CRDMO) globally, with more than 2,200 employees.  Our US operations are US headquartered in Irvine, CA. Our 7 global facilities provide integrated solutions and exceptional services to our clientele for challenging preclinical and clinical trial projects. With capabilities spanning Drug Discovery, Development, and Manufacturing, it is no surprise that BioDuro-Sundia is a leading partner of choice.

 

Why BioDuro-Sundia?

Take the next step in your career and join BioDuro-Sundia today to change lives through the products we help create. Here, you will contribute your talents to meaningful projects that impact the lives of patients around the world and develop as an individual by working directly with a team of seasoned experts and rising stars. Our values of Accountability, Respect, Tenacity, Results and Integrity are embedded in everything we do. No matter what your role may be, BioDuro-Sundia strives to ensure all our employees are empowered and given the necessary tools to lead us in our relentless pursuit of success.

Job Overview/Summary

Design synthetic route based on the desired payload-linker target molecules using SciFinder/Reaxys or AI design software. Strong ability of designing the efficient and convergent synthetic route. Skilled in literature search

Essential Functions and Responsibilities

· Familiarity with various payloads such as BCL-XL payloads, Auristatins, TLR7 Payloads, Steroid payloads, TLR8 payloads, TLR7/8 payloads, Sting payloads, Durocarmyclin analogues, Camptothecin analogues, Adriamycin analogues, etc. Be familiar with various linkers and the reaction types used for ADC Payload-linker synthesis

· Strong ability on the purification methods used for ADC Payload-linker purification. Strong capabilities in project trouble shooting: synthesis, purification, characterization, etc

· Support the daily work of the project leader and report the progress to the supervisor

· 50% time on the bench for trouble shooting, 50% time on team management

·  This job description is subject to change at any time.

Requirements

· Ph.D. degree in organic chemistry, or related fields, with more than 2 years of experience on ADC payload-linker synthesis

· Good English oral and writing communication skills

· Strong team management capability, be able to lead a team of 5-20 chemists

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