Senior Process Development Associate, Downstream

Encoded Therapeutics Inc. is a biotechnology company advancing precision medicines for a broad range of genetic disorders. Our mission is to unlock new opportunities for viral gene therapy through genomics-driven discovery. We focus on delivering life-changing advances for individuals with genetic disorders not addressable with current approaches. For more information, please visit www.Encoded.com.

This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of a diverse therapeutic pipeline driven by a transformative core technology. The position of Process Development Associate II / Senior PD Associate will join the Downstream Process Development group at Encoded Therapeutics. A qualified candidate will be responsible for execution of purification process development studies, and purification of samples supporting upstream PD. The ideal candidate will be hardworking, flexible, and able to work across multiple projects in a fast-paced and dynamic environment.

Workplace Model: On-Site

Responsibilities

• Develop and carry out bench scale unit operations for rAAV purification including chromatography, depth filtration, tangential flow-filtration, and viral filtration.
• Utilize analytical methods including ddPCR, ELISA, Refyn, Picogreen, Alkaline gel, CE-SDS, SEC-HPLC
• Analyze, interpret, and present process performance and product quality data.
• Meticulously maintain complete and accurate records of all work performed in an ELN.
• Contribute to authoring and reviewing technical reports and SOPs.
• Participate in process transfer activities

Requirements

• B.S. or M.S. in chemical engineering, biochemical engineering, biochemistry, or related field
• 3-6 years of industry experience in purification process development or similar role    
• Skill with chromatography instrumentation and control software, especially Äkta systems and UNICORN software
• Experience with running characterization and analytical assays
• Effective interpersonal communication and presentation skills
• Ability to write clear and concise technical documents
• Enthusiasm to work with a team to meet shared objectives
• Proficient with Microsoft Office suite including Excel, Powerpoint, and Word.

Preferred Qualifications

• Experience with AAV purification and quality parameters
• Capability to perform statistical data analysis, which may include DoE, use of JMP software
• Familiarity with Empower, SoftMax Pro, and other analytical assay software

The anticipated salary range for Senior Process Development Associate candidates who will work in California is $91,945 - $108,171. This position may also be filled at the Process Development Associate II level with an anticipated salary range of $77,775 - $91,500. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, education, etc. Encoded Therapeutics is a multi-state employer and this salary range may not reflect positions that work in other states.

A hired applicant may be eligible for an annual bonus as well as equity under the company’s stock plan.

Benefits

• Comprehensive benefits package, including competitive employer premium contributions
• Meaningful stock option grants
• PTO, sick time, and holiday pay
• Generous Parental Leave program
• Pre-tax medical and dependent care programs
• STD, LTD, Life and AD&D
• Professional development opportunities
• Team-building events
• Fully stocked kitchen
• Purple Tie dry cleaning service
• Fitness center

Employees (and their families) may obtain medical, dental, vision and basic life insurance benefits through the company and enroll in our company's 401k plan. Employees will also accrue vacation time off and paid sick time off and may become eligible for paid parental leave. Employees will also enjoy designated paid holidays throughout the calendar year.

Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.

If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.

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