Associate Director, Process Chemistry

We are seeking an experienced Associate Director or Director of Process Chemistry for Antibody-Drug Conjugates (ADC) to join our Biopharmaceutical Development team. In this critical role, you will lead the development and optimization of synthetic routes for ADC production, ensuring high quality and efficiency in our drug development processes.

Your key responsibilities will include:

• Leading a team of process chemists to design and optimize processes for ADC synthesis.
• Developing robust and scalable production processes, focusing on yield, purity, and cost-effectiveness.
• Collaborating closely with cross-functional teams including Analytical, Quality Assurance, and Regulatory Affairs to ensure compliance with industry standards.
• Driving innovation by evaluating new technologies and methodologies to enhance ADC production.
• Overseeing documentation and reporting of experimental work, ensuring adherence to GLP and GMP...

Frontier Medicines is seeking a highly motivated individual for a newly created Associate Director role in Process Chemistry in Frontier’s South San Francisco office. The successful candidate will lead internal and external resources to develop scalable manufacturing processes for Frontier’s small molecule pipeline. The role will include oversight of CDMOs from process chemistry development through to drug substance manufacturing.

Requirements

What will you be doing?

• Responsible for leading all small molecule drug substance development and manufacturing
• Management of drug substance process chemistry development, scale up, and manufacturing for GLP studies and GMP manufacturing at CDMOs
• Develop manufacturing processes that are scalable, safe, cost-effective, and environmentally friendly
• Responsible for CRO/CDMOs, including selection, technology transfer, and cGMP API manufacturing
• Leverage...